The Department of Pharmacology and Toxicology aims to develop and equip students with concrete foundations in basic pharmacology, toxicology, and pharmacootherapeutics so that ultimately they will practice rational prescribing as clinicians, actively participate in researches and provide extension services that will contribute to improvement in the quality of health care in the country.

Having realized the important role of the University as a public service institution, the Department aims to strengthen its extension services by engaging in projects and activities that have local, national and global impact.

Aside from extension services, the Department aims to produce quality researches whose output can be translated into policies as well as product development i.e. for safe, affordable, efficacious medicinal products. The Department also envisions being at par with current trends in molecular pharmacology and toxicology researches.

The Department envisions being a model academic unit in teaching pharmacology and toxicology utilizing modern methods of teaching such as blended and team-based approaches .

The Department envisions playing an active role in carving the nation’s drug policies, laws, and regulations, hence making a positive impact on our society.

The Philippine Medical School, the forerunner of the University of the Philippines College of Medicine, was established by virtue of the Second Philippine Commission Act 1415 dated December 1, 1905, as a response to the urgent need for more doctors in the country.  The school opened on June 10, 1907, occupying the old structure of the School for the Deaf and Blind on Bonifacio Drive (previously Malecon Drive) while its own building on Pedro Gil Street (previously Herran) was being constructed. On June 1, 1910, the school transferred to  its present site.. Three months after the transfer of the College at Pedro Gil Street, the Philippine General Hospital was opened and that became the University’s teaching hospital.
During the first five years of existence of the Philippine Medical School, Pharmacology as a subject was taught by the Department of Physiology. Lectures in pharmacology and toxicology were given in the first semester of the second year of the medical course, while pharmacy materiamedica and therapeutics were taken up in the third year.
A functionally independent Department of Pharmacology was created in 1912 with the reorganization of the UP College of Medicine. Its first head was Alfred O. Shaklee, an American. After eight years, Filipino pharmacologists began heading the department. The first was Dr. Daniel de la Paz, an exemplary professor who served the longest (29 years) as department chairman. Dr. De la Paz is thus, regarded as the father of Pharmacology in the Philippines.
Through the years, the department has developed undergraduate and graduate academic programs in basic and clinical pharmacology & toxicology for medical, nursing and dentistry students. It also offers a Master of Science in Pharmacology for graduates of medicine, veterinary medicine, pharmacy, biochemistry and biology courses. The Department, through its faculty, has achieved benchmarks in innovative postgraduate courses in basic and clinical pharmacology, in good clinical practice and good prescribing, and in pedagogy or teaching of pharmacology.
The research thrusts of the Department focused on basic pharmacology  studies  involving mechanisms of action, pharmacologic  effects and safety profile  of various medicinal plants, as well as pharmacologic benefits of marine organisms. The output of the researches on medicinal plants eventually have been transformed into medicines that are effective, safe, affordable and available to majority of Filipinos. Examples of these drugs are the Lagundi  for the relief of cough and asthma and Sambong as a diuretic and chemolysis of renal stones. The laboratory has also conducted clinical pharmacology and toxicology researches which led to the setting up of a biochemical laboratory for simple drug assays and toxicological studies. Other projects include the conduct of bioavailability/bioequivalence studies and drug evaluation which will help  ensure the quality and safety of generic drugs in the country.
In line with the university’s goal as a public service institution, the Department has been involved in several extension services through provision of direct services that improve the health conditions of people in economically challenged and high-risk communities exposed to hazardous substances; provision of new drug products from medicinal plants that are safe, efficacious, affordable and available; capacity building among colleagues in government service to improve the quality of health care; transfer of knowledge to colleagues in the health profession and other professions; participation in technical committees of regular agencies and attendance to senate/congress hearings on health-related issues for policy formulation, changes and implementation. Several of the faculty members are members of various agencies in the Department of Health and the Food and Drug Authority such as the Pesticide Policy Technical Advisory Committee, Fertilizer & Pesticide Authority; the DOH Formualry Executive Council and the UP NIH-FDA technical Review Committee. Other faculty members are involved in advocacies and extension services with global impact such as the European Union Chemical Biological Radiological and Nuclear (CBRN) Risk Mitigation Centres of Excellence Initiative, and the UPCM thrust of Patient Safety.

Through partnerships with government and international agencies, the Department through its faculty, is able to contribute to the wealth of knowledge in pharmacology and toxicology. More so, the partnerships have  paved the  way to resource and grants generation. For instance, because of assistance that the Department provides the Department of Health, the agency provides funding support to some activities of the Department.

The Department of Pharmacology and Toxicology has won the coveted Silver Cup award for the most Outstanding Basic Science Department of the UP College of Medicine 7 times for the following academic years: 1993-1994, 1997-1998, 1999-2000, 2002-2003, 2003-2004, 2011-2012 (awarded during the 100th year anniversary of the department) and the most recent  AY 2017-2018.

Courses for Doctor of Medicine

LU4       Therapeutics 201: Pharmacologic Basis of Therapeutics
LU5       Therapeutics 202: Pharmacotherapeutics
LU6       Therapeutics Conference


Pharma 221: Pharmacology of Disease Processes
Pharma 253.1 : Guide to Good Prescribing Part I
Pharma 254: Ethnopharmacology
Pharma 253.2: Guide to Good Prescribing Part II
Pharma 291: Research Elective in Pharmacology
Pharma 292: Clinical Elective in Pharmacology
Pharma 294: Community Pharmacology

MS Pharmacology

Pharma 201 and 202: Pharmacodynamics and Pharmacokinetics
Pharma 210: Readings in Advanced Pharma
Pharma 220: Pharmacologic Techniques
Pharma 234: Advanced Molecular Pharmacology
Pharma 235: Biologic Fate of Drugs
Pharma 236: Advanced Comparative Pharma and Pharmacogenetics
Pharma 241: Advanced Behavioral Pharma
Pharma 242: Advanced Muscle Pharmacology
Pharma 243: Teratology & Dev’tal Pharmacology
Pharma 244: Clinical Pharmacology
Pharma 245: Advances in Autonomic Pharma
Pharma 246: Endocrine Pharmacology
Pharma 247: Cancer Chemotherapy
Pharma 248: Toxicology
Pharma 250: Intro to Pharmacoepidemiology
Pharma 252: Intermediate Pharmacoepidemiology
Pharma 299: Research Methods in Pharma

N5: Nursing Pharmacology
Pharma 22: Pharmacology for Dentistry Students

Faculty and Staff of the Department of Pharmacology and Toxicology: At present, the pharmacology department has 17 faculty members, and the list includes 3 emeritus professors.

Chair: Cecilia A. Jimeno, MD

Dr. Stephanie Fay S. Cagayan (Vice- Chair and Assistant Chair for Academics)
Dr. Leonila A. Estole-Casanova (Assistant Chair for Services)
Dr. Nerissa M. Dando
Dr. Herbert Ho
Dr. Cleotilde H. How (Professor Emeritus)
Dr. Irma R. Makalinao
Dr. Nelia P. Cortes-Maramba (Professor Emeritus)
Dr. Cecilia Nelia C. Maramba-Lazarte (Assistant Chair for Research)
Dr. Raymond A. Oliva
Dr. Lynn Crisanta R. Panganiban
Dr. Jose Paciano T. Reyes (Assistant Chair for Academics)
Dr. Maria Concepcion C. Sison (Special Assistant to the Chair)
Dr. Richard Henry P. Tiongco
Dr. Ernesto V. Valdez (Professor Emeritus)
Dr. Cynthia I. Valencia (Clinical Professor)
Asst Professor Ailyn M. Yabes (Program Coordinator, MS Pharmacology)

Cross appointed Clinical Associate Professors:
Dr. Ma. Stella T. Giron (cross-appointed from UP NIH)
Dr. Jaime M. Purificacion (cross-appointed from UP NIH)

Administrative Staff:
Francesca Dorothy Que-Tan, University Research Associate)
Mr. Rosauro Hernando, Laboratory Technician 1
Mr. Celso Sabangan, Laboratory Aide
Criselyn Caraqueo, Administrative Assistant
Maria Isabel Miguel, Administrative Aide

Department of Pharmacology and Toxicology
UP College of Medicine
Telephone number: +632 5218251 (Fax) + 6325264248
Cell phone number: +63 922 8797398
Email: pharmafaculty@gmail.com

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